From MIT Technology Review
Vista Therapeutics is developing ultra-sensitive detectors.

By Katherine Bourzac

Physicians often test the levels of a few telltale blood proteins in seriously injured or ill patients to detect organ failure and other problems. Now Vista Therapeutics, a startup based in Santa Fe, NM, hopes to improve the care of these patients with sensitive devices for continuous bedside monitoring of such blood biomarkers. Instead of taking daily snapshots of the patient’s levels of blood proteins, the company’s nanosensors should allow for continuous monitoring of changes that occur over periods of only a few hours.

Spencer Farr, CEO of Vista Therapeutics, says that the first application of the technology will be for careful monitoring of patients whose status can change rapidly–such as those in the ICU after suffering a heart attack or traumatic injuries from a car accident. “We envision having a branch in the patient’s IV that tests continuously or every five to ten minutes,” says Farr. The nanowires are sensitive enough that they should be able to detect trace biomarkers that diffuse into the IV line from the blood. After a car wreck, for example, patients could be closely monitored for molecular warning signs of impending kidney and other organ failure.

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